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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3AP1
All Species:
10
Human Site:
T539
Identified Species:
36.67
UniProt:
Q6ZUJ8
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZUJ8
NP_689522.2
805
90398
T539
V
P
V
P
R
P
E
T
T
A
P
G
A
H
Q
Chimpanzee
Pan troglodytes
XP_507955
805
90393
T539
V
P
V
P
R
P
E
T
T
A
P
G
A
H
Q
Rhesus Macaque
Macaca mulatta
XP_001101530
805
90373
T539
V
P
V
P
R
P
E
T
T
A
S
G
A
H
Q
Dog
Lupus familis
XP_850837
806
90541
A539
V
P
V
P
R
P
E
A
N
A
S
G
T
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ32
811
90910
A539
V
P
V
P
R
P
E
A
S
A
P
G
P
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518515
526
58515
K281
V
E
T
V
D
M
L
K
S
H
I
K
E
E
L
Chicken
Gallus gallus
Q9DDT2
800
90138
S542
P
V
P
R
P
E
S
S
S
P
Q
P
D
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.3
91.8
N.A.
84.3
N.A.
N.A.
50.8
69.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.5
94.7
N.A.
90.6
N.A.
N.A.
56.8
80.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
66.6
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
73.3
N.A.
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
29
0
72
0
0
43
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
15
0
0
0
15
72
0
0
0
0
0
15
15
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
72
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
0
58
15
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
15
0
0
0
15
0
0
0
% K
% Leu:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
15
% L
% Met:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
15
0
0
0
0
15
0
% N
% Pro:
15
72
15
72
15
72
0
0
0
15
43
15
15
15
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
43
% Q
% Arg:
0
0
0
15
72
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
15
15
43
0
29
0
0
0
0
% S
% Thr:
0
0
15
0
0
0
0
43
43
0
0
0
15
0
0
% T
% Val:
86
15
72
15
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _